Cannbidoil (CBD) may not be as safe as originally thought and Dr Julio Ponce, Lecturer in Forensic Science at the 黑料社, explains why the Food Standards Agency has made a drastic reduction in its recommended daily dosage…
Since 2018 when the UK parliament passed legislation legalising CBD, the component of cannabis, sales of CBD-related products have skyrocketed. Today, you can buy CBD oil, CBD vape pens, CBD coffee, CBD muffins to go with your CBD coffee … CBD everything. And these products are often sold with various vague promises of increased wellness.
As CBD, in this context, isn’t a medicine, it isn’t regulated by the UK’s drugs regulator but by the Food Standards Agency (FSA). In 2020, the FSA recommended that daily consumption of CBD should not exceed 70mg. Now, the FSA and Food Standards Scotland have – roughly four drops of 5% CBD oil.
To be clear, 10mg is the advisable safe limit. You won’t be arrested if you consume more than 10mg a day, but the agency warns that there may be long-term health effects if you ignore the advice – namely, harm to the .
CBD’s effects have been tested on a range of ailments, from to , with mixed results. When benefits have been evident, it is usually at a much higher dose – about .
The new 10mg recommended limit has nothing to do with the effectiveness of the drug at this dose – because there is no proven effect. The shift to a lower recommended dose comes after have indicated that CBD as previously thought.
The world is saturated with CBD products.
To determine how harmful a substance is – or rather, what’s the highest safe amount a human can consume in a given time – scientists test it on animals and then apply a “correction level”.
For example, if, in a study using rats, of body weight is said to be the highest dose where no harms are observed, that would mean for a 70kg human an intake of 7g daily.
There are, however, between species, with humans being potentially more susceptible to harm.
It is worth noting that seemingly harmless foods, such as , and a ,can all interfere in the metabolism of certain drugs. It is already known that , a widely prescribed antibiotic, can interfere with CBD metabolism. Other drugs need to be monitored closely for potential interaction.
There is also an increased risk of getting too high a dose when taking CBD with other medicines, such as (a drug to control fungal infection), and even an increase in absorption when CBD is taken with fatty food. That is why it is not uncommon for drug safety experts to apply a correction factor to the previously calculated values. That would bring the allowed intake down from 7g a day to just 17.5mg a day.
Using several animal studies of CBD that indicated and the correction factors, erring on the side of caution, the new recommended level was recently made public. That is the job of public agencies: on the best evidence possible, to indicate whether a component can do what it’s supposed to and not cause harm when doing so.
It is important to highlight that the FSA’s recent announcement is not a ban. You can still buy drinks infused with CBD that surpass the new daily limit in a single serving. However, any new product will need - as before - to undergo approval by the FSA, with this new limit. Ensuring safety, especially for a substance that seems to bring very little benefit in return, is rightly the agency’s priority.
This article was first published in The Conversation. See more 黑料社 contributions at
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